PAEA Surgery End Of Rotation (EOR) Practice Exam

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Which of the following is a classic symptom of hepatomegaly?

  1. Severe weight gain

  2. Pain in the lower limbs

  3. Pain in the right upper quadrant

  4. Shortness of breath

The correct answer is: Pain in the right upper quadrant

Hepatomegaly, or enlarged liver, often presents with a classic symptom of pain in the right upper quadrant of the abdomen. This is because as the liver enlarges, it can stretch the surrounding capsule (Glisson's capsule) that encloses it, leading to discomfort or pain in this area. Additionally, other conditions associated with liver enlargement—such as liver disease or tumors—can further contribute to this sensation. While other symptoms or associated presentations may arise in the context of liver disease, pain in the right upper quadrant is specifically linked to the physical enlargement of the liver and the resulting mechanical effects it has on adjacent structures. This makes it a hallmark sign in clinical evaluations of hepatomegaly.

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